Stromal Collagenase in Melanoma: A Vascular Connection

Osteoprotegerin: osteo-vascular connection.

Regulation of corneal collagenase production: epithelial-stromal cell interactions.

Mixtures of epithelial and stromal cells isolated from normal adult rabbit cornea, when cocultured in the presence of cytochalasin B, produced latent collagenase, whereas neither cell type alone, nor the mixture in the absence of this agent, did so. The enzyme, a characteristic animal collagenase, required proteolytic activation. The relative concentrations of epithelial and stromal cells had a...

Adipose derived stromal vascular fraction improves early tendon healing: an experimental study in rabbits

Tendon never restores the complete biological and mechanical properties after healing. Bone marrow and recently adipose tissue have been used as the sources of mesenchymal stem cells, which have been proven to enhance tendon healing. Stromal vascular fraction (SVF), derived from adipose tissue by an enzymatic digestion, represents an alternative source of multipotent cells, which undergo differ...

Effects of Uncultured Adipose Derived Stromal Vascular Fraction on Tendon Healing in Rabbits: A Histological and Immunohistochemical Study

Objective- To evaluate the potential effects of uncultured adipose derived stromal vascular fraction on tendon healing. Design- Prospective descriptive study. Animals- Twenty five adult male New Zealand white rabbits, weighing 2.5-3.0 kg were used. Five rabbits were used as donors of adipose tissue and the rest were divided into control and treatment groups. Procedures- The injury model was ...

Experimental vascular lesions elicited by collagenase in rats.

Purified collagenase which attacks only native collagen and gelatin was injected intravenously into the normal and DCA hypertensive rats to determine whether damage in collagenous tissue of the vascular wall would result in diffuse necrotizing lesions of the vessels. In the normal rats subclinical edema, proteinuria, and mild degenerative lesions in the small arteries and arterioles were produc...